Cardiovascular Insufficiency, Abdominal Sepsis, and Patients’ Age Are Associated with Decreased Paraoxonase-1 (PON1) Activity in Critically Ill Patients with Multiple Organ Dysfunction Syndrome (MODS)

Figure 1

PON1 activities in healthy controls and MODS (a), the effect of the clinical type of MODS (b), and PON1 as a marker of MODS (c) and septic shock (d). Data on panels (a–b) presented as means with 95% CI and analyzed using the -test for independent samples. Data on panels (c–d) presented as ROC curves with 95% CI. The diagonal line represents the chance marker with no discriminative power (), and a grey dot represents an optimal cut-off value. MODS: multiple organ dysfunction syndrome. (a) Significantly different from healthy controls. (b) Significantly different from severe sepsis. AUC: area under the receiver operating characteristic (ROC) curve.

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