Cardiovascular Insufficiency, Abdominal Sepsis, and Patients’ Age Are Associated with Decreased Paraoxonase-1 (PON1) Activity in Critically Ill Patients with Multiple Organ Dysfunction Syndrome (MODS)
PON1 activities in healthy controls and MODS (a), the effect of the clinical type of MODS (b), and PON1 as a marker of MODS (c) and septic shock (d). Data on panels (a–b) presented as means with 95% CI and analyzed using the -test for independent samples. Data on panels (c–d) presented as ROC curves with 95% CI. The diagonal line represents the chance marker with no discriminative power (), and a grey dot represents an optimal cut-off value. MODS: multiple organ dysfunction syndrome. (a) Significantly different from healthy controls. (b) Significantly different from severe sepsis. AUC: area under the receiver operating characteristic (ROC) curve.