Cardiovascular Insufficiency, Abdominal Sepsis, and Patients’ Age Are Associated with Decreased Paraoxonase-1 (PON1) Activity in Critically Ill Patients with Multiple Organ Dysfunction Syndrome (MODS)
The association of mPON1 with the clinical type of MODS (a), cardiovascular insufficiency (b), and metabolic dysfunction (c) and its diagnostic power as a marker of septic shock (d), cardiovascular insufficiency (e), and metabolic dysfunction (f). Data on panels (a–c) presented as means with 95% CI and analyzed using the -test for independent samples. Data on panels (d-e) presented as ROC curves with 95% CI. The diagonal line represents the chance marker with no discriminative power (), and a grey dot represents an optimal cut-off value. AUC: area under the receiver operating characteristic (ROC) curve; CVI: cardiovascular insufficiency; MetDysf: metabolic dysfunction.