ABCB1 Polymorphisms and Drug-Resistant Epilepsy in a Tunisian Population

Table 12

Association of ABCB1 polymorphisms and drug resistance in epileptic syndrome subgroups.

Presence of syndrome		Drug-resistant patients ()		Drug-responsive patients ()		ORs	95% CI	value	^2
			%		%
ABCB1 C1236T genotypes	TT vs. CC+CT	11	57.895	0	0	20.294	1.014-406.357	0.049	7.020
	TT vs. CT	11	69.750	0	0	27.182	1.286-574.353	0.034	8.250
ABCB1 G2677T genotypes	TT vs. GT	9	64.286	0	0	22.455	1.051-479.955	0.046	7.010
ABCB1 C3435T genotypes	TT vs. CT	11	91.667	1	20	44.000	2.193-882.709	0.013	8.730

Values ( and %). ORs: odds ratio; 95% CI: confidence interval; significant value ≤ 0.05; ²: chi-square.