ABCB1 Polymorphisms and Drug-Resistant Epilepsy in a Tunisian Population

Table 5

Distribution of ABCB1 allele frequencies in drug-responsive and drug-resistant patients.

SNP	ABCB1 allele	Drug-resistant patients () (%)	Drug-responsive patients () (%)	ORs	95% CI	value	^2
ABCB1 C1236T	C	30	61	0.274	0.152-0.493	≤0.001	19.380
	T	70	39	3.650	2.029-6.563	≤0.001
ABCB1 G2677T	G	33	47	0.555	0.313-0.985	0.044	4.080
	T	67	53	1.801	1.016-3.192	0.044
ABCB1 C3435T	C	31	68	0.211	0.116-0.384	≤0.001	27.380
	T	69	32	4.730	2.604-8.591	≤0.001

Values ( and %). ORs: odds ratio; 95% CI: confidence interval; significant value ≤ 0.05; ²: chi-square.