Research Article
ABCB1 Polymorphisms and Drug-Resistant Epilepsy in a Tunisian Population
Table 9
Haplotype frequencies of the ABCB1 C1236T, G2677T, and C3435T polymorphisms in drug-responsive and drug-resistant patients.
| ABCB1 C1236T-G2677T-C3435T haplotype | Drug-resistant patients () | Drug-responsive patients () | ORs | 95% CI | value | 2 | | % | | % |
| CGC | 3 | 6 | 35 | 70 | 0.027 | 0.0073-0.1019 | ≤0.001 | 43.460 | TTC | 8 | 16 | 1 | 2 | 9.333 | 1.1210-77.7072 | 0.039 | 5.980 | TGC | 1 | 2 | 3 | 6 | 0.320 | 0.0321-3.1837 | 0.331 | 1.040 | CTT | 7 | 14 | 0 | 0 | 17.414 | 0.9665-313.7492 | 0.053 | 7.530 | CGT | 8 | 16 | 4 | 8 | 2.191 | 0.6145-7.8082 | 0.227 | 1.520 | TTT | 8 | 16 | 0 | 0 | 18.910 | 1.0607-337.1442 | 0.046 | 8.700 | CTC | 6 | 12 | 5 | 10 | 1.227 | 0.3490-4.3158 | 0.750 | 0.100 | TGT | 9 | 18 | 2 | 4 | 5.268 | 1.0766-25.7798 | 0.040 | 5.010 |
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Values ( and %). ORs: odds ratio; 95% CI: confidence interval; significant value ≤ 0.05; 2: chi-square. |