The Leukocyte VCS Parameters Compared with Procalcitonin, Interleukin-6, and Soluble Hemoglobin Scavenger Receptor sCD163 for Prediction of Sepsis in Patients with Cirrhosis

Table 3

Baseline characteristics, inflammatory marker, and VCS parameters.

	Group 1	Group 2	Group 3	All groups	value
	Sepsis ()	Infection ()	Ctr ()		1 vs. 2	1 vs. 3	2 vs. 3
Age (year)				NS	NS	NS	NS
Sex (m/f)	33/11	56/39	70/30	NS	NS	NS	NS
Procalcitonin (ng/mL)				<0.001	<0.05	<0.001	<0.001
IL-6 (pg/mL)				<0.001	<0.05	<0.001	<0.001
sCD163 (mg/L)				<0.001	NS	<0.001	<0.001
WBC (×10^9/mL)				<0.05	NS	<0.001	0.032
Neutrophil % (NE)				<0.05	NS	<0.001	<0.001
Monocyte % (MO)				NS	NS	NS	NS
VCS parameters
Neutrophils
Volume (MNV)				<0.001	NS	<0.001	<0.001
Conductivity (MNC)				0.073	NS	NS	NS
Scatter (MNS)				<0.05	NS	<0.05	<0.05
Monocytes
Volume (MMV)				<0.001	<0.001	<0.001	<0.05
Conductivity (MMC)				0.55	NS	NS	NS
Scatter (MMS)				<0.001	NS	<0.001	<0.001
Lymphocytes
Volume (MLV)				<0.001	NS	<0.05	<0.001
Conductivity (MLC)				0.19	NS	NS	NS
Scatter (MLS)				0.54	NS	NS	NS
Volume distribution width
Neutrophils (NDW)				<0.001	<0.05	<0.001	NS
Monocytes (MDW)				<0.001	<0.001	<0.001	NS

value < 0.05 (ANOVA with post hoc analysis) was considered statistically significant. NS: not significant; Ctr: cirrhosis patients with nonsepsis and no infections; IL-6: interleukin-6; sCD163: soluble hemoglobin scavenger receptor.