The Impact of Serum Glucose on the Predictive Value of Serum Lactate for Hospital Mortality in Critically Ill Surgical Patients

Table 3

Univariable and multivariable analysis of in-hospital mortality based on glucose levels.

(a)

Variable	Univariable regression		Multivariable regression
	OR (95%-CI)	value	OR (95%-CI)	value
Age	0.507 (0.221-1.163)	0.109
Gender	0.492 (0.214-1.132)	0.095
Reason for ICU admission
Cardiovascular disease	1.796 (0.701-4.601)	0.222
Gastrointestinal disease	0.879 (0.364-2.121)	0.773
Neurological disease	0.969 (0.300-3.315)	0.959
Respiratory disease	1.447 (0.609-3.441)	0.403
Surgery	1.360 (0.593-3.118)	0.467
Sepsis	1.040 (0.320-3.383)	0.948
Trauma	0.519 (0.112-2.406)	0.402
Other	2.917 (0.877-9.695)	0.081
Comorbidities
ACS	0.914 (0.187-4.475)	0.911
AKI	1.162 (0.423-3.192)	0.771
ALI	0.874 (0.234-3.266)	0.841
ARDS	2.619 (0.938-7.314)	0.066
Cirrhosis	0.393 (0.048-3.199)	0.383
Diabetes mellitus	3.363 (0.984-11.498)	0.053
DIC	4.250 (0.258-70.045)	0.312
Drinking	0.180 (0.041-0.798)	0.024	0.157 (0.018-1.399)	0.097
Hypertension	0.634 (0.238-1.690)	0.362
Malignant disease	2.308 (0.882-6.043)	0.089
MOF	2.550 (1.003-6.481)	0.049	1.443 (0.475-4.386)	0.517
Smoking	0.365 (0.139-0.962)	0.042	0.484 (0.115-2.041)	0.323
Stroke	0.613 (0.169-2.232)	0.458
APACHE II	1.083 (1.027-1.142)	0.003	1.043 (0.969-1.123)	0.262
Lactate	1.126 (1.042-1.216)	0.003	1.093 (1.007-1.188)	0.035
qSOFA	1.356 (0.862-2.132)	0.188
SOFA	1.147 (1.043-1.262)	0.005	1.104 (1.006-1.210)	0.036

(b)

Variable	Univariable regression		Multivariable regression
	OR (95%-CI)	value	OR (95%-CI)	value
Age	0.507 (0.221-1.163)	0.109
Gender	1.067 (0.301-3.785)	0.920
Reason for ICU admission
Cardiovascular disease	1.387 (0.310-6.216)	0.669
Gastrointestinal disease	0.312 (0.087-1.115)	0.073
Neurological disease	2.400 (0.489-11.772)	0.281
Respiratory disease	0.927 (0.216-3.986)	0.919
Surgery	0.732 (0.195-2.749)	0.644
Sepsis	0.542 (0.059-4.956)	0.587
Trauma	0.841 (0.155-4.554)	0.841
Other	—	—
Comorbidities
ACS	1.629 (0.356-7.456)	0.530
AKI	0.987 (0.179-5.450)	0.988
ALI	4.200 (0.735-23.991)	0.107
ARDS	0.841 (0.155-4.554)	0.841
Cirrhosis	0.854 (0.087-8.383)	0.892
Diabetes mellitus	2.891 (0.747-11.192)	0.124
DIC	—	—
Drinking	0.727 (0.136-3.880)	0.709
Hypertension	0.738 (0.175-3.124)	0.680
Malignant disease	0.137 (0.016-1.152)	0.067
MOF	2.889 (0.672-12.415)	0.154
Smoking	1.556 (0.395-6.131)	0.528
Stroke	3.909 (0.494-30.942)	0.197
APACHE II	1.144 (1.027-1.142)	0.005	1.126 (0.982-1.290)	0.089
Lactate	1.168 (0.928-1.470)	0.186
qSOFA	1.953 (0.891-4.279)	0.095
SOFA	1.229 (1.033-1.463)	0.020	1.041 (0.812-1.333)	0.753

(c)

Variable	Univariable regression		Multivariable regression
	OR (95%-CI)	value	OR (95%-CI)	value
Age	1.019 (0.984-1.050)	0.288
Gender	3.250 (0.965-10.950)	0.057
Reason for ICU admission
Cardiovascular disease	2.813 (0.718-11.021)	0.138
Gastrointestinal disease	0.698 (0.214-2.278)	0.552
Neurological disease	1.877 (0.509-6.921)	0.344
Respiratory disease	0.977 (0.281-3.398)	0.971
Surgery	0.642 (0.188-2.188)	0.479
Sepsis	0.727 (0.145-3.636)	0.698
Trauma	0	0.999
Other	1.047 (0.109-10.014)	0.968
Comorbidities
ACS	3.333 (0.823-13.494)	0.091
AKI	0.341 (0.041-2.840)	0.320
ALI	0.571 (0.066-4.983)	0.613
ARDS	0.492 (0.057-4.226)	0.518
Cirrhosis	1.050 (0.202-5.460)	0.954
Diabetes mellitus	1.513 (0.420-5.447)	0.526
DIC	0	0.999
Drinking	1.432 (0.439-4.673)	0.552
Hypertension	1.391 (0.453-4.268)	0.564
Malignant disease	1.324 (0.408-4.295)	0.641
MOF	1.476 (0.353-6.166)	0.593
Smoking	1.062 (0.332-3.404)	0.919
Stroke	1.476 (0.353-6.166)	0.593
APACHE II	1.087 (1.017-1.161)	0.014	1.056 (0.962-1.158)	0.252
Lactate	1.154 (1.035-1.285)	0.010	1.118 (0.997-1.255)	0.057
qSOFA	1.783 (0.940-3.383)	0.077
SOFA	1.157 (1.026-1.305)	0.017	1.039 (0.876-1.233)	0.658