Disease Markers / 2019 / Article / Tab 1

Research Article

Prognostic Value of Combined Analysis of CTLA-4 and PLR in Esophageal Squamous Cell Carcinoma (ESCC) Patients

Table 1

Univariate and multivariate Cox regression analyses estimating the risk factors of OS in ESCC patients.

VariableUnivariate analysesMultivariate analyses
HR95% CI valueHR95% CI value

Gender0.3890.094-1.6120.193
Age0.6830.268-1.7380.424
KPS1.2370.674-2.2710.493
Drinking0.9430.505-1.7600.854
Smoking1.4490.762-2.7560.258
Weight loss1.1160.579-2.1520.742
Histological grade0.8320.454-1.5270.553
Location2.7060.652-11.2370.171
Length1.9910.949-4.1770.069
T stage2.7181.250-5.9130.0123.1680.320-31.3760.324
N stage3.4641.841-6.5170.0005.1940.547-49.2650.151
TNM stage2.2181.428-3.1710.0000.5370.064-4.5080.567
Resection margin0.9350.226-3.8750.926
Adjuvant radiotherapy2.1071.116-3.9780.0222.1041.109-3.9930.023
Adjuvant chemotherapy1.8290.941-3.5560.075
T-CTLA-4(-) +PLR (-)2.0311.083-3.8070.0272.0251.071-3.8260.030

Abbreviations: OS: overall survival; ESCC: esophageal squamous cell carcinoma; HR: hazard ratio; CI: confidence interval; KPS: Karnofsky; T-CTLA-4: tumor cell cytotoxic T-lymphocyte-associated antigen-4; PLR: platelet lymphocyte ratio.