Prognostic Value of Combined Analysis of CTLA-4 and PLR in Esophageal Squamous Cell Carcinoma (ESCC) Patients

Table 2

Clinicopathological characteristics of ESCC patients.

Clinicopathological characteristics		T-CTLA-4(-) +PLR (-)	Other	value
Gender
Male	66	30	36
Female	6	2	4	0.686
Age (years)
<70	62	27	35
≥70	10	5	5	0.703
KPS
>80%	39	17	22
≤80%	33	15	18	0.874
Weight loss (kg)
<5	50	22	28
≥5	22	10	12	0.909
Drinking
Yes	32	13	19
No	40	19	21	0.560
Smoking
Yes	46	21	25
No	26	11	15	0.784
Histological differentiation
Well and moderate	39	15	24
Poor	33	17	16	0.267
Location
Proximal third	7	3	4
Middle third	43	17	26
Distal third	22	12	10	0.513
Tumor length (cm)
<3	18	10	8
≥3	54	22	32	0.273
Infiltration depth
T1 and T2	21	11	10
T3 and T4	51	21	30	0.384
Lymph node status
N0	47	23	24
N1	25	9	16	0.293
pTNM staging
I and II	48	23	25
III	24	9	15	0.402
Resection margin
Positive	3	1	2
Negative	69	31	38	1.000
Adjuvant radiotherapy
Yes	19	7	12
No	53	25	28	0.437
Adjuvant chemotherapy
Yes	16	5	11
No	56	27	29	0.228

Abbreviations: T-CTLA-4: tumor cell cytotoxic T-lymphocyte-associated antigen-4; PLR: platelet lymphocyte ratio; ESCC: esophageal squamous cell carcinoma; KPS: Karnofsky.