Review Article
Role of MicroRNA-124 as a Prognostic Factor in Multiple Neoplasms: A Meta-Analysis
Table 2
Essential features and overall survival of the studies contained in this meta-analysis.
| Study | Year | High expression | Low expression | OS | DFS/PFS | Nationality | Malignant disease | Source of HR | HR | LL | UL | value | HR | LL | UL | value |
| Zheng | 2011 | 65 | 66 | NM | | | | 0.400 | 0.200 | 0.800 | 0.009 | China | HCC | Reported | Wang | 2012 | 25 | 71 | 0.216 | 0.081 | 0.578 | 0.002 | 0.221 | 0.084 | 0.577 | 0.002 | China | Colorectal | Reported | Takafumi | 2014 | 25 | 24 | 0.147 | 0.008 | 0.789 | 0.022 | 0.624 | 0.291 | 1.300 | 0.209 | Japan | Colorectal | SC | Chen | 2014 | 69 | 68 | 0.550 | 0.300 | 0.990 | 0.001 | 0.560 | 0.320 | 0.970 | 0.002 | China | Glioma | Reported | Henriett | 2015 | NM | NM | 0.385 | 0.138 | 0.912 | 0.032 | 0.485 | 0.169 | 1.205 | 0.121 | Canada | ccRCC | Reported | Dong | 2015 | 67 | 66 | 0.316 | 0.110 | 0.559 | 0.017 | NM | | | | China | Breast cancer | SC | Han | 2015 | 53 | 52 | 0.680 | 0.290 | 1.600 | 0.005 | NM | | | | China | Osteosarcoma | Reported | Li | 2014 | 48 | 116 | 0.136 | 0.034 | 0.534 | 0.004 | 0.168 | 0.044 | 0.644 | 0.009 | China | NSCLC | Reported | Wang | 2014 | 32 | 33 | 0.652 | 0.461 | 0.922 | 0.015 | NM | | | | China | PDAC | SC | Zhang | 2015 | 46 | 46 | 0.340 | 0.150 | 0.730 | <0.05 | 0.300 | 0.120 | 0.730 | <0.05 | China | NSCLC | SC | Cui | 2016 | 15 | 15 | 0.800 | 0.240 | 2.680 | <0.05 | NM | | | | China | NSCLC | SC | Dong | 2016 | 20 | 20 | 0.610 | 0.110 | 3.330 | 0.002 | 0.630 | 0.150 | 2.610 | 0.006 | Japan | Cervical cancer | Reported | Feng | 2016 | 24 | 24 | 0.506 | 0.201 | 1.274 | 0.015 | NM | | | | China | Breast cancer | Reported | Li | 2016 | 57 | 70 | 0.362 | 0.135 | 0.974 | 0.044 | NM | | | | China | Cervical cancer | Reported | Sun | 2016 | 18 | 35 | 0.405 | 0.247 | 0.800 | 0.001 | NM | | | | China | PDAC | SC | Xu | 2016 | 20 | 20 | 0.890 | 0.200 | 3.920 | 0.017 | NM | | | | China | HCC | Reported | Wu | 2017 | NM | NM | 0.452 | 0.373 | 0.568 | 0.002 | NM | | | | China | HCC | Reported | Jin | 2017 | 96 | 99 | 0.330 | 0.190 | 0.500 | <0.01 | NM | | | | China | NSCLC | Reported | Cong | 2017 | 55 | 59 | 0.282 | 0.177 | 0.725 | 0.019 | 0.255 | 0.156 | 0.637 | 0.012 | China | Osteosarcoma | SC | Li | 2017 | 40 | 48 | 0.424 | 0.260 | 0.670 | <0.05 | NM | | | | China | Gastric cancer | Reported | Luo | 2017 | NM | NM | 0.680 | 0.520 | 0.730 | 0.023 | NM | | | | China | NSCLC | Reported | Yulia | 2017 | 17 | 50 | 5.400 | 1.800 | 16.000 | 0.002 | 2.400 | 1.000 | 5.700 | 0.050 | Israel | Ependymoma | Reported | Long | 2018 | NM | NM | 0.659 | 0.523 | 0.830 | 0.036 | 0.460 | 0.230 | 0.950 | 0.026 | China | HCC | SC | Liu | 2018 | 51 | 70 | 0.550 | 0.270 | 1.110 | 0.002 | 0.620 | 0.330 | 1.180 | 0.009 | China | Gastric cancer | Reported |
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NM: not mentioned; SC: survival curve; Colorectal: colorectal cancer.
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