Role of MicroRNA-124 as a Prognostic Factor in Multiple Neoplasms: A Meta-Analysis

Table 3

Essential features and methylation outcomes of studies used in this meta-analysis.

Study	Year	Methylation	Nonmethylation	OS				RFS/DFS				Nationality	Malignant disease	Type of miR-124	Source of HR
				HR	LL	UL	value	HR	LL	UL	value
Xabier	2009	208	145	1.770	0.850	3.670	<0.001	2.400	1.050	2.480	<0.001	Spain	ALL	miR-124a	SC
Gebauer	2013	NM	NM	NM				9.3700	2.680	32.800	<0.001	Germany	ccRCC	miR-124-3	Reported
Wang	2014	33	32	1.838	0.973	3.470	0.092	NM				China	PDAC	miR-124-1	SC
Wang	2014	34	31	3.055	1.596	5.850	0.002	NM				China	PDAC	miR-124-2	Reported
Wang	2014	33	32	2.499	1.313	4.757	0.017	NM				China	PDAC	miR-124-3	Reported
Kim	2017	48	109	1.690	0.990	2.890	0.053	NM				Korea	NSCLC	miR-124-1	Reported
Kim	2017	78	79	1.990	1.190	3.320	0.009	NM				Korea	NSCLC	miR-124-2	Reported
Kim	2017	81	76	2.100	1.240	3.550	0.006	NM				Korea	NSCLC	miR-124-3	Reported
Wang	2017	23	33	2.110	0.970	4.600	0.025	NM				China	MDS	miR-124-1	SC
Wang	2017	29	27	2.100	0.840	5.290	0.004	NM				China	MDS	miR-124-2	SC
Wang	2017	35	21	1.810	0.690	4.730	0.010	NM				China	MDS	miR-124-3	SC