Serum Exosomal miRNAs Are Associated with Active Pulmonary Tuberculosis

Figure 1

Characterization of the serum exosomes. (a) Transmission electron microscopy showing that serum exosomes are spherical particles with an average size of 70 nm. The bar represents 100 nm. (b) Detection of exosomal CD81 surface markers using flow cytometry. MFI (mean fluorescence intensity) represents the expression of CD81 on the surface of exosomes. The results are representative of three independent experiments. (c) Exosomal RNA analysis by Agilent Bioanalyzer indicated a population of 18–28 nt without prominent ribosomal RNA peaks. Results are representative of three independent experiments.

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