Research Article

PTPN22 Gene Polymorphisms Are Associated with Susceptibility to Large Artery Atherosclerotic Stroke and Microembolic Signals

Table 6

The risk of rs2488457 for LAAS according to age, gender, and BMI.

FactorsGenotypeMultivariate analysis
Adjusted OR (95% CI)
value

Age
 <65CC1.000 (reference)-
CG+GG1.347 (0.874-2.076)0.177
 ≥65CC1.000 (reference)-
CG+GG1.454 (0.688-2.011)0.169
Gender
 MaleCC1.000 (reference)-
CG+GG1.207 (0.824-1.734)0.101
 FemaleCC1.000 (reference)-
CG+GG1.311 (0.490-3.511)0.590
BMI
 <24 kg/m2CC1.000 (reference)-
CG+GG1.533 (0.993-2.368)0.054
 ≥24 kg/m2CC1.000 (reference)-
CG+GG1.273 (0.551-2.941)0.571

BMI: body mass index; multivariate analysis (covariates: sex, age, history of smoking and drinking, hypertension, diabetes, dyslipidemia, and family history of ischemic stroke events).