PTPN22 Gene Polymorphisms Are Associated with Susceptibility to Large Artery Atherosclerotic Stroke and Microembolic Signals
Table 6
The risk of rs2488457 for LAAS according to age, gender, and BMI.
Factors
Genotype
Multivariate analysis Adjusted OR (95% CI)
value
Age
<65
CC
1.000 (reference)
-
CG+GG
1.347 (0.874-2.076)
0.177
≥65
CC
1.000 (reference)
-
CG+GG
1.454 (0.688-2.011)
0.169
Gender
Male
CC
1.000 (reference)
-
CG+GG
1.207 (0.824-1.734)
0.101
Female
CC
1.000 (reference)
-
CG+GG
1.311 (0.490-3.511)
0.590
BMI
<24 kg/m2
CC
1.000 (reference)
-
CG+GG
1.533 (0.993-2.368)
0.054
≥24 kg/m2
CC
1.000 (reference)
-
CG+GG
1.273 (0.551-2.941)
0.571
BMI: body mass index; multivariate analysis (covariates: sex, age, history of smoking and drinking, hypertension, diabetes, dyslipidemia, and family history of ischemic stroke events).