Prognostic Value of MicroRNA-497 in Various Cancers: A Systematic Review and Meta-Analysis

Table 2

Main results of pooled HRs in the meta-analysis.

Comparisons	Heterogeneity test			Pooled HR (95% CI)	Hypothesis test		No. of studies
			(%)
OS
Total	13.71	0.47	0	2.19 (1.84, 2.60)	8.89	<0.001	15
Ethnicity
Asian	8.94	0.71	0	2.10 (1.76, 2.51)	8.19	<0.001	13
Caucasian	1.62	0.20	38	4.06 (2.00, 8.24)	3.89	<0.001	2
Cancer type
HCC	0.25	0.62	0	2.35 (1.58, 3.50)	4.21	<0.001	2
Other cancers	13.30	0.35	10	2.15 (1.78, 2.60)	7.84	<0.001	13
DFS/RFS
Total	12.92	0.005	77	1.17 (0.53, 2.57)	0.39	0.69	4
Ethnicity
Asian	9.99	0.007	80	1.42 (0.55, 3.67)	0.73	0.47	3
Caucasian	—	—	—	0.63 (0.27, 1.47)	1.07	0.29	1

OS: overall survival; DFS: disease-free survival; RFS: relapse-free survival; HCC: hepatocellular carcinoma; HR: hazard ratio; CI: confidence interval.