Response to: Comment on “Pretreatment Hepatitis C Virus NS5A/NS5B Resistance-Associated Substitutions in Genotype 1 Uruguayan Infected Patients”

<div>Substitution saturation analysis using DAMBE. (a) NS5A Uruguayan strain dataset; (b) NS5B Uruguayan strain dataset. Transitions (blue line) and transversions (green line) are plotted against divergence. The genetic distance was computed with the GTR nucleotide substitution model. The results show that all Uruguayan sequences included in our study [<a href="/journals/dm/2019/2520302/#B2">2</a>] contain enough evolutionary information for reliable phylogenetic inferences and little substitution saturation despite corresponding to chronic HCV strains.</div>

Disease Markers

fig2

Figure 2

Figure 2: Response to: Comment on “Pretreatment Hepatitis C Virus NS5A/NS5B Resistance-Associated Substitutions in Genotype 1 Uruguayan Infected Patients” 

Figure 2 | Response to: Comment on “Pretreatment Hepatitis C Virus NS5A/NS5B Resistance-Associated Substitutions in Genotype 1 Uruguayan Infected Patients” 