Immune Exclusion Is Frequent in Small-Cell Carcinoma of the Bladder

Table 1

Total T cell, cytotoxic T cell, and PD-1-positive T cell densities at the invasive margin (IM) and the center of the tumor (CT) in two patients with adjacent areas of small-cell and urothelial cell bladder cancer.

Patient	Small-cell part			Urothelial part
	CD3^+ (cells/mm^2)	CD8^+ (cells/mm^2)	PD-1^+ (cells/mm^2)	CD3^+ (cells/mm^2)	CD8^+ (cells/mm^2)	PD-1^+ (cells/mm^2)
No. 8
IM	1328	254	676	1355	628	764
CT	109	13	7	1063	823	545
No. 4
IM	1526	394	873	1097	234	824
CT	50	23	38	466	78	385