CSF-1 Overexpression Predicts Poor Prognosis in Upper Tract Urothelial Carcinomas
(a) Comparison with CSF-1 levels in 35 pairs of upper tract urothelial carcinomas (UTUC) and the corresponding cancer-adjacent normal tissues. The CSF-1 expression level was significantly higher in UTUC than in the normal urothelium (paired Wilcoxon signed-rank test, ). (b) Immunohistochemistry staining for CSF-1 in UTUC and normal urothelium. (×200). (c) CSF-1 mainly localized in the nucleus of BFTC909 and UM-UC-14 cancer cells. Analysis of CSF-1 intracellular localization by immunofluorescence. Routinely cultured cells were subjected to immunofluorescence using an anti-CSF-1 antibody and nucleus stained with the DAPI. (upper panels: ×400, lower panels: ×200).