Disease Markers / 2019 / Article / Tab 2

Research Article

CSF-1 Overexpression Predicts Poor Prognosis in Upper Tract Urothelial Carcinomas

Table 2

Univariate and multivariate analyses of disease-free survival and cancer-specific survival for upper tract urothelial carcinomas.

VariablesItemDisease-free survivalCancer-specific survival
UnivariateMultivariateUnivariateMultivariate
HR95% CI valueHR95% CI valueHR95% CI valueHR95% CI value

StageIII/IV1.761.01-3.080.0461.180.57-2.440.6616.032.17-16.800.0014.181.00-17.510.051
I/II1.001.001.001.00

GradeHigh1.150.61-2.170.6591.050.50-2.220.9021.650.55-4.990.3760.630.14-2.860.547
Low1.001.001.001.00

GenderMale1.240.71-2.160.4561.180.64-2.160.5961.360.55-3.360.5010.890.32-2.430.815
Female1.001.001.001.00

Age (years)≥651.680.92-3.050.0911.540.78-3.070.2161.430.54-3.770.4701.110.33-3.720.870
<651.001.001.001.00

Tumor locationRenal pelvis + ureter1.390.68-2.830.3641.470.64-3.370.3651.110.37-3.320.8561.330.31-5.820.701
Renal pelvis0.760.40-1.450.4060.670.34-1.310.2430.560.19-1.680.3010.420.13-1.340.143
Ureter1.001.001.001.00

Tumor sideLeft0.800.46-1.400.4430.840.46-1.550.5840.590.24-1.480.2630.430.14-1.290.131
Right1.001.001.001.00

Lymphovascular invasionPositive1.350.72-2.550.3511.130.54-2.390.7452.490.97-6.340.0572.150.69-6.700.186
Negative1.001.001.001.00

Creatinine (mg/dl)>1.51.060.60-1.880.8440.930.50-1.730.8220.760.29-2.000.5700.590.19-1.760.342
≤1.51.001.001.001.00

CSF-1High2.141.20-3.810.0102.561.30-5.040.0075.181.71-15.710.0045.141.27-20.840.022
Low1.001.001.001.00

Abbreviations: HR: hazard ratio; CI: confidence interval.