Research Article
Zonulin Family Peptide Levels in Ascites and Serum in Patients with Liver Cirrhosis: A Preliminary Study
Table 1
Characteristics of the study group and the controls. Data is presented as mean value with 95% confidence interval or median with quartiles (1-3Q)
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| | Parameters | Study group
| Controls
| value |
| | Age (years) | 68 (61-75) | 42 (35-49) | <0.001 | | Sex (men/women) | 11/13 | 4/14 | 0.12 | | Hb (g/dL) | 11.6 (10.4-12.7) | 14.3 (13.9-14.7) | <0.001 | | PLT (103/μL) | 178 (114-282) | 305 (253-370) | <0.01 | | WBC (103/μL) | 10.2 (8.0-12.3) | 7.2 (5.9-8.5) | 0.03 | | ALT (U/L) | 24.3 (17.2-31.5) | 27.9 (25.2-30.6) | 0.39 | | INR | 1.53 (1.15-1.99) | 0.95 (0.80-1.00) | <0.001 | | Serum protein (g/dL) | 58.6 (56.1-61.2) | 74.3 (71.7-76.9) | <0.001 | | Serum albumin (g/dL) | 26.6 (24.1-29.2) | 42.3 (39.7-44.9) | <0.001 | | C-reactive protein (mg/L) | 36.9 (20.8-59.0) | <5 | <0.001 | | Serum creatinine (mg/dL) | 1.56 (0.92-2.21) | 0.86 (0.78-0.94) | 0.06 | | Serum bilirubin (mg/dL) | 3.07 (1.94-4.20) | 0.96 (0.89-1.02) | < 0.001 | | Serum ZFPs (ng/mL) | 30.5 (23.6-35.6) | 62.0 (47.6-67.4) | <0.001 | | Ascites ZFPs (ng/mL) | 12.1 (0.25-18.8) | — | — |
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ZFPs: zonulin family peptides.
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