Zonulin Family Peptide Levels in Ascites and Serum in Patients with Liver Cirrhosis: A Preliminary Study

Table 2

Comparison of patients with low and high “zonulin family peptides” in ascites. Data is presented as mean value with 95% confidence interval or median with quartiles (1-3Q).

Parameters	Low ZFP levels	High ZFP levels	value
Age (years)	62 (52-84)	70 (59-79)	0.70
Sex (men/women)	3/5	8/8	0.57
Hb (g/dL)	9.8 (7.8-13.2)	13.1 (11.4-13.6)	0.21
PLT (10^3/μL)	130 (107-178)	218 (156-319)	0.06
WBC (10^3/μL)	10.5 (5.1-12.6)	9.0 (5.9-12.5)	0.83
ALT (U/L)	21.5 (14.0-43.5)	19.5 (10.0-31.5)	0.38
Serum protein (g/dL)	58.8 (58.0-63.5)	58.0 (53.1-62.7)	0.61
Serum albumin (g/dL)	26.8 (26.0-31.5)	26.0 (21.1-30.9)	0.61
C-reactive protein (mg/L)	22.4 (21.2-50.9)	41.0 (26.5-118.7)	0.11
Serum creatinine (mg/dL)	1.25 (0.55-1.45)	1.35 (0.84-1.70)	0.38
Serum bilirubin (mg/dL)	2.34 (1.67-5.12)	2.39 (0.89-4.03)	0.42
Serum ZFPs (ng/mL)	23.3 (17.9-27.0)	33.5 (29.7-43.6)	<0.001
Ascites ZFPs (ng/mL)	0.25 (0.25-0.27)	16.4 (12.1-21.6)	<0.001
Ascites/serum ZFPs	0.011 (0.010-0.014)	0.462 (0.387-0.569)	<0.001
Transudate/exudate ()	6/2	7/9	0.16
The causes of liver cirrhosis ()
Inflammatory	2	0
Alcoholic	5	6	0.02
Mix	1	1
Unknown	0	9
Child-Pugh score ()
Class A	1	0
Class B	3	9	0.30
Class C	4	7
MELD score (pts)	19.5 (10.0-29.1)	20.5 (14.7-26.3)	0.85
pts ()	3 (37%)	8 (50%)	0.56