An Angiotensinogen Gene Polymorphism (rs5050) Is Associated with the Risk of Coronary Artery Aneurysm in Southern Chinese Children with Kawasaki Disease
Table 2
Genotype distributions of the AGT gene polymorphism and Kawasaki disease susceptibility.
Genotype/allele
Cases ()
Controls ()
a
Crude OR (95% CI)
Adjusted OR (95% CI)b
b
rs699 ()
AA
15 (1.97)
21 (2.16)
1.00
1.00
AG
200 (26.32)
269 (27.67)
1.04 (0.52-2.07)
0.91
1.05 (0.52-2.08)
0.899
GG
545 (71.71)
682 (70.16)
1.12 (0.57-2.19)
0.745
1.13 (0.58-2.22)
0.719
Additive
0.776
1.07 (0.89-1.29)
0.418
1.08 (0.89-1.30)
0.439
Dominant
745 (98.03)
951 (97.84)
0.786
1.10 (0.56-2.14)
0.788
1.12 (0.57-2.16)
0.767
Recessive
215 (28.29)
290 (29.84)
0.482
1.08 (0.89-1.33)
0.438
1.09 (0.88-1.34)
0.44
A
230 (15.13)
311 (16.00)
0.486
G
1290 (84.87)
1633 (84.00)
rs5050 ()
TT
537 (70.66)
681 (70.06)
1.00
1.00
TG
203 (26.71)
263 (27.06)
0.98 (0.79-1.12)
0.846
0.98 (0.79-1.21)
0.835
GG
20 (2.63)
28 (2.88)
0.91 (0.51-1.62)
0.742
0.91 (0.51-1.64)
0.763
Additive
0.934
0.97 (0.81-1.16)
0.739
0.97 (0.51-1.64)
0.743
Dominant
223 (29.34)
291 (29.94)
0.786
0.97 (0.79-1.20)
0.789
0.97 (0.79-1.20)
0.784
Recessive
740 (97.37)
944 (97.12)
0.754
0.91 (0.51-1.63)
0.756
0.92 (0.51-1.65)
0.778
T
1277 (84.01)
1625 (83.59)
0.738
G
243 (15.99)
319 (16.41)
a test of the genotype distributions between the Kawasaki disease patients and controls. bAdjusted for age and sex.
