Disease Markers / 2019 / Article / Tab 2

Research Article

An Angiotensinogen Gene Polymorphism (rs5050) Is Associated with the Risk of Coronary Artery Aneurysm in Southern Chinese Children with Kawasaki Disease

Table 2

Genotype distributions of the AGT gene polymorphism and Kawasaki disease susceptibility.

Genotype/alleleCases ()Controls ()aCrude OR (95% CI)Adjusted OR (95% CI)bb

rs699 ()
 AA15 (1.97)21 (2.16)1.001.00
 AG200 (26.32)269 (27.67)1.04 (0.52-2.07)0.911.05 (0.52-2.08)0.899
 GG545 (71.71)682 (70.16)1.12 (0.57-2.19)0.7451.13 (0.58-2.22)0.719
 Additive0.7761.07 (0.89-1.29)0.4181.08 (0.89-1.30)0.439
 Dominant745 (98.03)951 (97.84)0.7861.10 (0.56-2.14)0.7881.12 (0.57-2.16)0.767
 Recessive215 (28.29)290 (29.84)0.4821.08 (0.89-1.33)0.4381.09 (0.88-1.34)0.44
 A230 (15.13)311 (16.00)0.486
 G1290 (84.87)1633 (84.00)
rs5050 ()
 TT537 (70.66)681 (70.06)1.001.00
 TG203 (26.71)263 (27.06)0.98 (0.79-1.12)0.8460.98 (0.79-1.21)0.835
 GG20 (2.63)28 (2.88)0.91 (0.51-1.62)0.7420.91 (0.51-1.64)0.763
 Additive0.9340.97 (0.81-1.16)0.7390.97 (0.51-1.64)0.743
 Dominant223 (29.34)291 (29.94)0.7860.97 (0.79-1.20)0.7890.97 (0.79-1.20)0.784
 Recessive740 (97.37)944 (97.12)0.7540.91 (0.51-1.63)0.7560.92 (0.51-1.65)0.778
 T1277 (84.01)1625 (83.59)0.738
 G243 (15.99)319 (16.41)

a test of the genotype distributions between the Kawasaki disease patients and controls. bAdjusted for age and sex.

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