An Angiotensinogen Gene Polymorphism (rs5050) Is Associated with the Risk of Coronary Artery Aneurysm in Southern Chinese Children with Kawasaki Disease
Table 4
Stratification analysis of the association between the rs5050T>G polymorphism and coronary artery aneurysm among patients with Kawasaki disease.
Variables
TT
TG/GG
Crude OR (95% CI)
Adjusted ORa (95% CI)
a
CAA/NCAA
Age, month
≤12
24/131
19/51
2.03 (1.03-4.03)
0.042
1.94 (0.98-3.87)
0.059
>12
40/340
21/134
1.33 (0.76-2.34)
0.32
1.32 (0.75-2.32)
0.343
Sex
Female
20/153
14/59
1.82 (0.86-3.83)
0.117
1.85 (0.87-3.90)
0.109
Male
44/318
26/126
1.49 (0.89-2.52)
0.14
1.42 (0.83-2.41)
0.197
Coronary artery outcomes
GCAA
14/185
21/471
1.70 (0.81-3.84)
0.137
1.35 (0.81-3.36)
0.167
MCAA
15/185
18/471
2.12 (1.05-4.30)
0.037
1.91 (0.924-3.95)
0.080
SCAA
11/185
24/471
1.17 (0.56-2.43)
0.68
1.01 (0.48-2.18)
0.961
GCAA: giant coronary artery aneurysm; MCAA: medium coronary artery aneurysm; SCAA: small coronary artery aneurysm. aAdjusted for age and sex.
