Disease Markers / 2019 / Article / Tab 2

Research Article

Prognostic Value of MicroRNAs in Patients after Myocardial Infarction: A Substudy of PRAGUE-18

Table 2

Relationship between individual marker levels and one-year mortality.

MarkerGeneConcentrationPatients, number (%)Survivors, number (%)Nonsurvivors, number (%) value
Locus (OMIM)

MicroRNAs (relative concentration)

miR-133aMIR133A1/MIR133A2<0.33093 (76.2)91 (78.4)2 (33.3)0.028
18q11.2/20q13.33≥0.33029 (23.8)25 (21.6)4 (66.7)

miR-1MIR1-1/MIR1-2<0.03178 (63.9)76 (65.5)2 (33.3)0.187
20q13.33/18q11.2≥0.03144 (36.1)40 (34.5)4 (66.7)

miR-499MIR499<0.08863 (51.6)63 (54.3)0 (0.0)0.011
20q11.22≥0.08859 (48.4)53 (45.7)6 (100.0)

Standard biomarkers (concentration in ng/L)

hsTnTTNN2<154.577 (63.6)75 (65.2)2 (33.3)0.189
1q32.1≥154.544 (36.4)40 (34.8)4 (66.7)

NT-proBNPNPPB<891.566 (54.1)66 (56.9)0 (0.0)0.008
1p36.22≥891.556 (45.9)50 (43.1)6 (100.0)

Fisher exact test. NT-proBNP = N-terminal prohormone of brain natriuretic peptide; hsTnT = high-sensitivity troponin.

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