Evaluation of Metabolic Defects in Fatty Acid Oxidation Using Peripheral Blood Mononuclear Cells Loaded with Deuterium-Labeled Fatty Acids

Figure 1

Precursor ion mass spectra observed in acylcarnitine analysis by MS/MS. Homogenized PBMCs loaded with d₃₁-hexadecanoic acid were subjected to acylcarnitine analysis. (a) Healthy control, (b) CPT-II deficiency, and (c) VLCAD deficiency. Stable isotope-labeled acylcarnitines as internal standards.

(a)

(b)

(c)