Research Article

Altered Levels of mRNAs for Calcium-Binding/Associated Proteins, Annexin A1, S100A4, and TMEM64, in Peripheral Blood Mononuclear Cells Are Associated with Osteoporosis

Table 3

Summary of statistical analysis on participants with no osteoporosis treatment.

mRNACompared sample groups ( = number of participants)95% confidence interval value (Bonferroni correction)

Annexin A1Nonosteoporotic control () vs. osteopenia ()0.18 to 0.478<0.0001
Nonosteoporotic control () vs. osteoporosis ()0.232 to 0.603<0.0001
Osteoporosis () vs. osteopenia ()-0.248 to 0.0710.272

TMEM64Nonosteoporotic control () vs. osteopenia ()-0.00096 to 0.07840.056
Nonosteoporotic control () vs. osteoporosis ()0.011 to 0.1090.0168
Osteoporosis () vs. osteopenia ()-0.063 to 0.020.305

S100A4Nonosteoporotic control () vs. osteopenia ()-0.273 to 0.5560.498
Nonosteoporotic control () vs. osteoporosis ()-0.124 to 0.9060.134
Osteoporosis () vs. osteopenia ()-0.694 to 0.1950.267