Metabolomics Analysis in Serum from Patients with Colorectal Polyp and Colorectal Cancer by ¹H-NMR Spectrometry

Figure 2

(a–c) OPLS-DA score plots derived from NMR spectra of serum samples and (d–f) the corresponding loading plots used to identify differential metabolites. (a, d) Colorectal polyps vs. controls; (b, e) CRC vs. control; (c, f) CRC vs. colorectal polyps. The gradient red color indicates that the variables are very significant ( in (d), in (e), and in (f); ); gradient orange indicates that the variables are significant ( in (d), in (e), and in (f); ); blue indicates that the variables are insignificant (NS).

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