Investigating the Protein Signature of Adamantinomatous Craniopharyngioma Pediatric Brain Tumor Tissue: Towards the Comprehension of Its Aggressive Behavior

Table 2

List of the pathways resulting from PANTHER database pathway overrepresentation analysis.

PANTHER pathways	Homo sapiens—REFLIST (21042)	Client text box input (436)	Client text box input (expected)	Client text box input (over/under)	Client text box input (fold enrichment)	Client text box input (raw value)	Client text box input (FDR)
Pentose phosphate pathway (P02762)	8	5	0.17	+	30.16
Glycolysis (P00024)	20	10	0.41	+	24.13
ATP synthesis (P02721)	7	3	0.15	+	20.68
TCA cycle (P00051)	10	3	0.21	+	14.48
Plasminogen-activating cascade (P00050)	18	4	0.37	+	10.72
Blood coagulation (P00011)	46	9	0.95	+	9.44
Parkinson disease (P00049)	103	16	2.13	+	7.5
FAS signaling pathway (P00020)	34	5	0.7	+	7.1
Cytoskeletal regulation by Rho GTPase (P00016)	84	12	1.74	+	6.89
Huntington disease (P00029)	145	17	3	+	5.66
Dopamine receptor-mediated signaling pathway (P05912)	58	6	1.2	+	4.99
Integrin signalling pathway (P00034)	190	14	3.94	+	3.56
Unclassified (UNCLASSIFIED)	18438	311	382.04	—	0.81

Referred to the experimental protein UniProt accession input list on PANTHER analysis tool.