Research Article
Severity of Vitamin D Deficiency Predicts Mortality in Ischemic Stroke Patients
Table 5
Results of crude and age-adjusted univariable Cox proportional hazard regression for composite end point.
| | Cox proportional hazard—crude analysis | Cox proportional hazard—age adjusted | HR | 95% CI | | | | HR | 95% CI | | | |
| years | 2.40 | 1.52–3.77 | <0.001 | 1.45 | 0.23 | — | — | — | — | — | Female vs. male | 1.41 | 0.91–2.18 | 0.12 | 0.38 | 0.54 | 1.09 | 0.69–1.74 | 0.69 | 0.14 | 0.70 | Diabetes | 1.66 | 1.08–2.56 | <0.05 | 1.98 | 0.16 | 1.48 | 0.96–2.28 | 0.07 | 1.42 | 0.23 | Hypertension | 0.86 | 0.48–1.52 | 0.61 | 1.23 | 0.27 | 0.71 | 0.40–1.28 | 0.26 | 0.99 | 0.32 | Atrial fibrillation | 1.47 | 0.94–2.28 | 0.09 | 0.05 | 0.82 | 1.10 | 0.69–1.75 | 0.67 | 0.15 | 0.69 | Ischemic heart disease | 1.56 | 1.01–2.44 | <0.05 | 0.01 | 0.91 | 1.37 | 0.87–2.16 | 0.17 | 0.01 | 0.92 | Valvular diseases | 1.72 | 0.93–3.17 | 0.08 | 0.22 | 0.64 | 1.49 | 0.80–2.76 | 0.21 | 0.34 | 0.56 | Previous stroke | 1.02 | 0.60–1.71 | 0.95 | 1.28 | 0.26 | 0.91 | 0.54–1.53 | 0.72 | 1.27 | 0.26 | Hypercholesterolemia | 0.81 | 0.49–1.33 | 0.40 | 0.09 | 0.76 | 0.85 | 0.52–1.39 | 0.52 | 0.11 | 0.74 | pg/mL | 1.56 | 0.97–2.52 | 0.07 | 0.27 | 0.60 | 1.37 | 0.84–2.22 | 0.20 | 0.63 | 0.43 | pg/mL | 0.86 | 0.56–1.31 | 0.48 | 0.02 | 0.89 | 0.88 | 0.57–1.35 | 0.57 | 0.01 | 0.97 | mL/min/1. 73 m2 | 1.63 | 1.06–2.51 | <0.05 | 0.05 | 0.83 | 1.25 | 0.79–1.96 | 0.33 | 0.25 | 0.61 | ng/mL | 2.38 | 1.41–4.01 | <0.01 | 0.53 | 0.47 | 2.26 | 1.34–3.81 | <0.01 | 0.37 | 0.54 | mg/L | 1.47 | 0.92–2.35 | 0.10 | 0.04 | 0.84 | 1.27 | 0.80–2.04 | 0.31 | 0.01 | 0.97 | Modified Rankin scale (mRS) at | 3.04 | 1.67–5.52 | <0.001 | 3.14 | 0.07 | 2.96 | 1.63–5.39 | <0.001 | 2.64 | 0.10 | mRS at | 6.54 | 4.24–10.09 | <0.001 | 9.26 | <0.01 | 5.68 | 3.57–9.03 | <0.001 | 7.91 | <0.01 | mRS at with time | 1.04 | 1.01–1.08 | <0.05 | — | — | 1.04 | 0.99–1.08 | 0.08 | — | — | 25-OH-D 20–29.9 ng/mL | 1.88 | 0.99–3.56 | 0.05 | 2.88 | 0.41 | 1.82 | 0.96–3.46 | 0.07 | 2.24 | 0.52 | 25-OH-D 10–19.9 ng/mL | 3.96 | 1.83–8.58 | <0.001 | 3.72 | 1.71–8.10 | <0.01 | ng/mL | 8.87 | 4.14–19.00 | <0.001 | 6.96 | 3.20–15.11 | <0.001 | NIHSS-I at admission (pts) | 1.08 | 1.04–1.13 | <0.001 | 0.43 | 0.51 | 1.07 | 1.03–1.12 | <0.01 | 0.30 | 0.58 |
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