Altered Serum MicroRNA Profile May Serve as an Auxiliary Tool for Discriminating Aggressive Thyroid Carcinoma from Nonaggressive Thyroid Cancer and Benign Thyroid Nodules

Table 2

MiRNA levels in the PTC, benign nodule, and the healthy control groups in the validation set by qRT-PCR^a.

miRNA	PTC ()	Benign nodule ()	Healthy control ()	value^b	value^c	value^d
miR-222-3p				0.536	<0.001	<0.01
miR-17-5p				0.391	<0.05	<0.001
miR-451a				0.188	<0.001	<0.001
miR-146a-5p				0.128	<0.01	0.092
miR-132-3p				0.247	<0.001	<0.001
miR-183-3p				0.619	<0.001	<0.001

PTC: papillary thyroid cancer. ^aThe relative contents of miRNAs are normalized to let-7d/g/i and presented as the . ^bDifference between the PTC group and the benign nodule group. ^cDifference between the PTC group and the healthy control group. ^dDifference between the benign nodule group and the healthy control group.