Biological Analysis of Gene Expression and Clinical Variables Suggest FZD1 as a Novel Biomarker for Patients with Kashin-Beck Disease, an Endemic Osteoarthritis in China

Table 6

Differential expression rate of nine differentially expressed genes in patients with KBD grades I and II.

Gene	Grade I		Grade II				OR
	+	−	+	−
ATR	3	27	33	17	23.76	0.001	17.4 (4.62 ± 65.96)
CSGALNACT	8	22	48	2	42.92	0.001	66.0 (12.93 ± 336.71)
CTSC	8	22	49	1	46.57	0.001	134.7 (15.87 ± 1143.71)
COL1A1	9	21	48	2	39.87	0.001	56.0 (11.13 ± 281.76)
FZD1	9	21	49	1	43.48	0.001	114.3 (13.61 ± 960.45)
GDF5	9	21	49	1	43.48	0.001	114.3 (13.61 ± 960.45)
SLC14A1	1	29	33	17	30.13	0.001	56.2 (7.05 ± 449.51)
SSBP1	9	21	48	2	39.87	0.001	56.0 (11.13 ± 281.76)
TNFSF11	1	29	32	18	28.47	0.001	51.5 (6.47 ± 410.79)

OR: odds ratios.