Exploring the Diagnostic Potential of Serum Golgi Protein 73 for Hepatic Necroinflammation and Fibrosis in Chronic HCV Infection with Different Stages of Liver Injuries

Table 3

Correlation between serum GP73 level and clinical characteristics (rho).

Parameters	Cohort A ()		Cohort B ()
	Rho	value	Rho	value
Parameters for liver injury
ALT	0.262	0.003	0.258	0.004
AST	0.526	<0.001	0.278	0.002
GGT	0.557	<0.001	0.186	0.041
TBA	0.378	<0.001	0.180	0.049
Necroinflammation activity grade ()	0.364	<0.001	0.297	0.001
Parameters for liver fibrosis
PLT	-0.373	<0.001	-0.392	<0.001
Fibrosis stage ()	0.484	<0.001	0.269	0.003
APRI	0.584	<0.001	0.345	<0.001
FIB-4	0.580	<0.001	0.380	<0.001
Parameters for liver function
TBIL	0.136	0.122	0.009	0.924
ALB	-0.431	<0.001	-0.389	<0.001
PT	0.374	<0.001	0.228	0.012
PA	-0.537	<0.001	-0.464	<0.001

GP73: Golgi protein 73; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma glutamyltransferase; TBA: total bile acid; PLT: platelet; APRI: AST-to-platelet ratio index; FIB-4: fibrosis index based on four factors; TBIL: total bilirubin; ALB: albumin; PT: prothrombin time; PA: prealbumin.