Evaluation of CERS2 Gene as a Potential Biomarker for Bladder Cancer

Figure 2

Effect of CERS2 knockdown on cellular migration in UMUC1 cells. (a) Fold change differences in the expression of CERS2 between siRNA-mediated CERS2-knockdown UMUC1 cells relative to the nontargeting siRNA-transfected negative control at 24, 48, and 72 hours posttransfection. (b) The percentage of gap closure of CERS2 knockdown versus negative control UMUC1 cells (200x magnification). CERS2-knockdown UMUC1 cells have significantly reduced migratory potential after 6 hours postscratch, corresponding to 30 hours post CERS2-siRNA transfection.

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