Human Epididymis Protein 4 (HE4) Reference Limits in Polish Population of Healthy Women, Pregnant Women, and Women with Benign Ovarian Tumors

Table 2

HE4 in healthy patients and in those with an ovarian benign tumor by age decades.

Age category (years)	Number of patients	Patients free of adnexal changes		Patients with benign adnexal changes
		Median (pmol/l)	Range (min–max); (pmol/l)	Median (pmol/l)	Range (min–max); (pmol/l)
16-19	11	42.0	43 – 60	48	34 - 67
20-29	75	40.5	15 – 61	52.0	33 - 94
30-39	80	45.0	32 – 79	54.0	31 - 212
40-49	107	48.0	24 – 92	53.0	25 - 95
50-59	107	51.0	24 – 118	58.0	41 - 101
60-69	63	52.0	40 – 120	67.0	33 - 120
70-79	15	62.0	48 – 188	96.5	44 - 209
80-83	2	—	—	119.5	98 - 141