Human Epididymis Protein 4 (HE4) Reference Limits in Polish Population of Healthy Women, Pregnant Women, and Women with Benign Ovarian Tumors

Table 3

Reference range of HE4 for healthy patients and for the extended group that includes those with benign adnexal changes.

Studied group	Menopausal status	Median (pmol/l)	Number of patients	HE4 norm (pmol/l) (CL95%)
Healthy women	All	48	265	33-85
Healthy women	Pre	44	157	15-73
Healthy women	Post	53	108	38-93
Healthy+benign conditions	All	49.5	460	33-91.5
Healthy+benign conditions	Pre	40	296	32-79
Healthy+benign conditions	Post	55	164	40-117
Patients with endometrial cysts	All	52	72	35-83
Patients with cystadenomas	All	52	51	34-119
Patients with dermoid cysts	All	53	39	33-94
Patients with serous cysts	All	51	33	37-79