Disease Markers / 2019 / Article / Tab 1

Research Article

What Is the Biological Function of Uric Acid? An Antioxidant for Neural Protection or a Biomarker for Cell Death

Table 1

Top 20 pathways with significance could be associated with the level of uric acid in different organs.

IDDescriptionSignificantAnnotated value valuePositive num.Negative num.

ko03010Ribosome184/1937288/76041.26E-443.37E-4217212
ko04141Protein processing in the endoplasmic reticulum89/1937172/76048.09E-141.09E-116227
ko00240Pyrimidine metabolism50/1937106/76049.93E-078.89E-053614
ko04975Fat digestion and absorption24/193739/76041.99E-060.000134213
ko00520Amino sugar and nucleotide sugar metabolism27/193749/76048.96E-060.000481198
ko05110Vibrio cholerae infection28/193752/76041.11E-050.0004941414
ko00230Purine metabolism68/1937170/76041.88E-050.0007213830
ko00480Glutathione metabolism28/193754/76042.80E-050.000941217
ko00983Drug metabolism (other enzymes)22/193739/76043.73E-050.001011193
ko03460Fanconi anemia pathway27/193752/76043.77E-050.001011189
ko03008Ribosome biogenesis in eukaryotes37/193781/76045.99E-050.0014622512
ko00620Pyruvate metabolism23/193743/76047.72E-050.0017271013
ko00330Arginine and proline metabolism28/193759/76040.0002090.0042781711
ko00500Starch and sucrose metabolism21/193740/76040.0002230.004278129
ko03030DNA replication20/193738/76040.0003010.00538164
ko00900Terpenoid backbone biosynthesis14/193723/76040.0003420.005742104
ko00561Glycerolipid metabolism26/193756/76040.0005340.008435197
ko04972Pancreatic secretion40/193798/76040.0005870.008748337
ko04113Meiosis (yeast)26/193759/76040.0014030.019819197
ko04111Cell cycle (yeast)29/193770/76040.0024430.032791245
ko00970Aminoacyl-tRNA biosynthesis21/193747/76040.0032070.03985129
ko00510N-Glycan biosynthesis22/193750/76040.0032660.03985193
ko02020Two-component system10/193717/76040.0035640.04159364
ko04110Cell cycle45/1937123/76040.0039050.043679423
ko04210Apoptosis33/193785/76040.0044400.0453372112
ko03440Homologous recombination14/193728/76040.0044760.045337104
ko00100Steroid biosynthesis11/193720/76040.0045600.045337110
ko04910Insulin signaling pathway48/1937134/76040.0047380.0454211929
ko00564Glycerophospholipid metabolism35/193792/76040.0050610.0468412312
ko03060Protein export12/193723/76040.0054100.04840384

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