Vitamin D Deficiency Predicts Poor Clinical Outcomes in Heart Failure Patients Undergoing Cardiac Resynchronization Therapy

Figure 1

Impact of baseline vitamin D on five-year mortality and clinical response. Receiver operating characteristic analysis was performed for determining the optimal cutoff point for baseline plasma vitamin D levels. The odds and hazard ratios refer to the presence versus the absence of a baseline plasma . (a) We compared the Kaplan-Meier survival curves by the log-rank test in patient groups of baseline plasma vitamin D levels below and over 24.13 ng/mL. We tested the 5-year mortality by using Cox regression analysis. (b) Clinical response, defined as a relative increase of at least 15% in the LVEF 6 months after implantation, was visualized by the contingency bar plot. We tested the lack of clinical response by using logistic regression analysis. HR: hazard ratio; OR: odds ratio; AUC: area under the curve; NPV: negative predictive value; PPV: positive predictive value.

(a)

(b)