Disease Markers / 2019 / Article / Tab 1 / Research Article
Association of Single-Nucleotide Polymorphism REX1 rs6815391, OCT4 rs13409 or rs3130932, and CTBP2 rs3740535 with Primary Lung Cancer Susceptibility: A Case-Control Study in a Chinese Population Table 1 Demographic characteristics of the included patients and healthy control.
Variable Case group (%) Control group (%) OR (95% CI) Age ≤52 295 (26.3) 289 (25.8) 1.000 53-59 285 (25.4) 273 (24.4) 1.012 (0.802-1.278) 60-66 272 (24.3) 274 (24.4) 0.973 (0.770-1.228) ≥67 269 (24.0) 285 (25.4) 0.925 (0.733-1.167) Gender Male 797 (71.1) 797 (71.1) 1.000 Female 324 (28.9) 324 (28.9) 1.000 (0.833-1.200) Degree of education Primary school or below 564 (50.4) 418 (37.3) 1.000 Junior and senior high school 443 (39.6) 553 (49.3) 0.594 (0.497-0.709) College degree or above 114 (10.2) 150 (13.4) 0.563 (0.428-0.741) Marital status Married 1054 (94.0) 1039 (92.7) 1.000 Others 64 (5.7) 66 (5.9) 0.956 (0.671-1.362) Single 3 (0.3) 16 (1.4) 0.185 (0.054-0.636) BMI (kg/m2) <18.5 124 (11.1) 51 (4.5) 1.000 18.5-23.9 694 (61.9) 613 (54.7) 0.466 (0.330-0.657) ≥24 303 (27.0) 457 (40.8) 0.273 (0.191-0.390) Pollution near the place of residence Not 900 (80.3) 1026 (91.5) 1.000 Exist 221 (19.7) 95 (8.5) 2.652 (2.052-3.428) House type Bungalow 377 (33.6) 182 (16.2) 1.000 Building 734 (65.5) 931 (83.1) 0.381 (0.311-0.466) Others 10 (0.9) 8 (0.7) 0.603 (0.234-1.555) Ventilation situation Well 859 (76.6) 990 (88.3) 1.000 General 223 (19.9) 115 (10.3) 2.235 (1.753-2.849) Worse 39 (3.5) 16 (1.4) 2.809 (1.559-5.063) Cooking oil fume (COF) No 190 (16.9) 350 (31.2) 1.000 Little 613 (54.7) 544 (48.5) 2.076 (1.681-2.563) Some 269 (24.0) 205 (18.3) 2.417 (1.876-3.114) Much 49 (4.4) 22 (2.0) 4.103 (2.407-6.992) Kitchen ventilator No 480 (42.8) 337 (30.1) 1.000 Yes 641 (57.2) 784 (69.9) 0.574 (0.482-0.683) Decoration within 10 years No 674 (60.1) 692 (61.7) 1.000 Yes 447 (39.9) 429 (38.3) 1.070 (0.903-1.268) Smoking No 425 (37.9) 659 (58.8) 1.000 Yes 696 (62.1) 462 (41.2) 2.336 (1.972-2.767) Passive smoking No 335 (29.9) 621 (55.4) 1.000 Yes 786 (70.1) 500 (44.6) 2.914 (2.449-3.467) Drink alcohol No 733 (65.4) 805 (71.8) 1.000 Yes 388 (34.6) 316 (28.2) 1.348 (1.127-1.613) Drink tea No 566 (50.5) 537 (47.9) 1.000 Yes 555 (49.5) 584 (52.1) 0.902 (0.764-1.064) History of lung disease No 983 (87.7) 1025 (91.4) 1.000 Yes 138 (12.3) 96 (8.6) 1.499 (1.139-1.973) Family history of cancer No 900 (80.3) 950 (84.7) 1.000 Yes 221 (19.7) 171 (15.3) 1.364 (1.095-1.699)
BMI = weight (kg)/height2 (m2 ).