Association of Single-Nucleotide Polymorphism REX1 rs6815391, OCT4 rs13409 or rs3130932, and CTBP2 rs3740535 with Primary Lung Cancer Susceptibility: A Case-Control Study in a Chinese Population

Table 3

Association of another three SNPs with susceptibility to lung cancer.

	Classification	Case (%)	Control (%)	OR (95% CI)	aOR (95% CI)^#
		rs6815391
Codominant	TT	477 (46.8)	472 (45.7)	1.000	1.000
	CT	438 (42.9)	435 (42.1)	0.996 (0.829-1.197)	0.901 (0.732-1.109)
	CC	105 (10.3)	126 (12.2)	0.825 (0.618-1.100)	0.925 (0.670-1.279)
Dominant	TT	477 (46.8)	472 (45.7)	1.000	1.000
	CT+CC	543 (53.2)	561 (54.3)	0.958 (0.805-1.139)	0.906 (0.745-1.102)
Recessive	TT+CT	915 (89.7)	907 (87.8)	1.000	1.000
	CC	105 (10.3)	126 (12.2)	0.826 (0.628-1.087)	0.973 (0.715-1.323)
Additive				0.936 (0.823-1.065)	0.942 (0.814-1.089)
rs3740535
Codominant	GG	602 (57.4)	614 (56.9)	1.000	1.000
	AG	373 (35.6)	401 (37.1)	0.949 (0.792-1.136)	0.916 (0.747-1.124)
	AA	73 (7.0)	64 (6.0)	1.163 (0.817-1.657)	1.067 (0.714-1.594)
Dominant	GG	602 (57.4)	614 (56.9)	1.000	1.000
	AG+AA	446 (42.6)	465 (43.1)	0.978 (0.824-1.162)	0.937 (0.772-1.139)
Recessive	AG+GG	975 (93.0)	1015 (94.0)	1.000	1.000
	AA	73 (7.0)	64 (6.0)	1.187 (0.839-1.680)	1.103 (0.744-1.636)
Additive				1.013 (0.882-1.163)	0.974 (0.833-1.139)
rs3130932
Codominant	TT	453 (43.4)	453 (41.8)	1.000	1.000
	GT	460 (44.0)	494 (45.7)	0.931 (0.776-1.117)	0.890 (0.725-1.093)
	GG	132 (12.6)	135 (12.5)	0.978 (0.744-1.285)	1.031 (0.757-1.404)
Dominant	TT	453 (43.4)	453 (41.8)	1.000	1.000
	GT+GG	592 (56.6)	629 (58.2)	0.941 (0.793-1.118)	0.919 (0.757-1.116)
Recessive	GT+TT	913 (87.4)	947 (87.5)	1.000	1.000
	GG	132 (12.6)	135 (12.5)	1.014 (0.785-1.311)	1.095 (0.819-1.463)
Additive				0.972 (0.857-1.101)	0.977 (0.848-1.125)

^#By the degree of education, marital status, BMI, pollution near the place of residence, house type, ventilation situation, COF, kitchen ventilator, smoking, passive smoking, drink alcohol, history of lung disease, and family history of cancer adjusted.