HMGB1 as a Potential Biomarker and Therapeutic Target for Malignant Mesothelioma

Figure 1

Schematic representation of HMGB1-involved mechanisms in asbestos-induced MM. See detail in text. HM cells: human mesothelial cells; MM: malignant mesothelioma; EMT: epithelial-to-mesenchymal transition; RAGE: the receptor for advanced glycation end products; TLRs: the Toll-like family of receptors.