Comparison of Performance of Equations for Estimated Glomerular Filtration Rate in Chinese Patients with Biopsy-Proven Diabetic Nephropathy
Table 3
Multivariable logistic regression of advanced glomerular classification and IFTA.
Variables
Glomerular classification of III and IV
IFTA of 2 and 3 scores
Odds ratio
95% CI
Odds ratio
95% CI
Gender (male)
0.349
0.174-0.700
0.003
1.037
0.538-2.000
NS
Age
0.985
0.955-1.015
NS
0.985
0.956-1.015
NS
Systolic blood pressure
1.008
0.991-1.025
NS
1.004
0.988-1.020
NS
Diastolic blood pressure
0.995
0.966-1.025
NS
1.015
0.987-1.043
NS
Diabetic duration
1.003
0.999-1.008
NS
1.001
0.997-1.005
NS
Triglyceride
0.905
0.769-1.063
NS
0.941
0.803-1.104
NS
Total cholesterol
1.022
0.821-1.271
NS
1.249
1.009-1.545
0.041
Proteinuria
1.059
0.979-1.146
NS
1.018
0.949-1.092
NS
Serum creatinine
1.004
0.993-1.015
NS
1.012
1.002-1.023
0.024
Cystatin C
3.771
1.140-12.472
0.030
1.680
0.576-4.902
NS
Gender and cystatin C were independently associated with advanced glomerular classifications (III and IV stages); total cholesterol and serum creatinine were independently associated with higher IFTA scores. IFTA: interstitial fibrosis and tubular atrophy; CI: confidence interval; NS: not significant. A two-tailed was considered statistically significant.
