Prognostic Value of the Systemic Inflammation Response Index in Patients with Adenocarcinoma of the Oesophagogastric Junction: A Propensity Score-Matched Analysis
Table 4
Univariate and multivariate Cox regression analyses for overall survival in patients with adenocarcinoma of oesophagogastric junction (matched datasets, 1 : 1).
Variables
Univariate analysis
Multivariate analysis
HR (95% CI)
value
HR (95% CI)
value
Sex
Female vs. male
1.16 (0.72-1.84)
0.540
—
—
Age
>60 vs. ≤60
1.09 (0.74-1.62)
0.656
—
—
Grade
0.043
0.491
Well
Ref.
Ref.
Moderately
4.56 (1.12-18.56)
0.034
1.71 (0.38-7.67)
0.486
Poorly
5.23 (1.25-21.99)
0.024
1.35 (0.29-6.36)
0.703
Tumour size
>5 cm vs. ≤5 cm
1.52 (1.04-1.98)
0.041
1.01 (0.66-1.54)
0.96
AJCC TNM stage
<0.001
<0.001
I
Ref.
Ref.
II
1.92 (0.99-3.71)
0.053
1.77 (0.88-3.56)
0.107
III
6.01 (3.36-10.74)
<0.001
4.97 (2.61-9.46)
<0.001
Vascular invasion
Yes vs. no
4.50 (2.58-7.88)
<0.001
2.38 (1.32-4.29)
0.004
SIRI
>0.68 vs. ≤0.68
1.67 (1.13-2.47)
0.010
1.51 (1.02-2.24)
0.040
AJCC: American Joint Committee on Cancer; SIRI: systemic inflammation response index; HR: hazard ratio; CI: confidence interval; Ref.: reference.
