Research Article
Associations of Common Variants in HFE and TMPRSS6 Genes with Hepcidin-25 and Iron Status Parameters in Patients with End-Stage Renal Disease
Table 3
Gender-related characteristics in patients with ACD (ESRD).
| | Characteristic | Females () | Males () | |
| | Age (years) | 58.50 (43.25-66.00) | 62.00 (47.25-67.75) | 0.165 | | Serum urea (mmol/L) | 19.85 (16.27-23.80) | 19.95 (17.90-23.08) | 0.530 | | Serum creatinine (μmol/L) | 715.50 (518.50-852.7) | 801.50 (661.50-979.25) | 0.006 | | eGFR (mL/min/1.73 m2) | 5.00 (4.00-7.00) | 6.00 (5.00-7.75) | 0.060 | | Hepcidin-25 (ng/mL) | 61.13 (22.94-110.62) | 47.37 (13.93-110.91) | 0.358 | | Hemoglobin (g/L) | 101.75 (93.25-108.90) | 107.25 (98.02-117.57) | 0.012 | | Serum iron (μmol/L) | 12.95 (10.30-15.70) | 11.20 (9.02-15.35) | 0.091 | | TIBC (μmol/L) | 38.80 (34.40-46.45) | 42.40 (36.65-48.17) | 0.132 | | Transferrin (g/L) | 1.65 (1.50-1.95) | 1.77 (1.57-1.91) | 0.379 | | TS (%) | 29.00 (21.45-38.35) | 30.10 (24.47-37.25) | 0.641 | | sTfR (mg/L) | 1.28 (1.08-1.73) | 1.18 (0.82-1.56) | 0.106 | | Ferritin (μg/L) | 304.20 (99.95-616.95) | 214.90 (77.75-548.73) | 0.455 | | CRP (mg/L) | 2.00 (1.35-4.67) | 4.20 (2.00-10.15) | 0.006 | | RBC (×1012/L) | 3.38 (3.02-3.58) | 3.49 (3.24-3.94) | 0.018 | | WBC (×109/L) | 6.31 (5.40-7.21) | 6.75 (5.62-8.20) | 0.141 | | MCV (fL) | 94.94 (92.51-97.83) | 93.12 (90.01-96.28) | 0.027 | | RDW (fL) | 14.72 (13.84-16.54) | 15.27 (14.04-16.26) | 0.317 |
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Continuous variables were presented as median (interquartile range); ESRD: end-stage renal disease; eGFR: estimated glomerular filtration rate; TIBC: total iron-binding capacity; TS: transferrin saturation; sTfR: soluble transferrin receptor; CRP: C-reactive protein; RBC: red blood cell count; WBC: white blood cell count; MCV: mean corpuscular volume; RDW: red cell distribution width.
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