Research Article

Red Cell Distribution Width and Platelet Count as Biomarkers of Pulmonary Arterial Hypertension in Patients with Connective Tissue Disorders

Table 2

Main features of the PH control group. We report the main features of the control group with PH of other etiologies. Categorical variables are shown as frequencies (%); continuous variables are shown as medians (IQR).

Variables

PH class (1/2/3/4/5)17 (28.8)/10 (16.9)/7 (12.0)/10 (16.9)/15 (25.4)
Age (years)73 (64-79)
Gender (F/M)33 (56)/26 (44)
Hb (g/dl)12.9 (11.9-14.8)
RDW (%)14.8 (13.2-17.0)
PLTs (×109/l)222 (184-266)
BNP (pg/ml)182.5 (77.7-299.5)
Creatinine clearance (ml/min)70.0 (51.0-87.0)
DLCO (ml/min/mmHg)53.0 (42.0-80.0)
FEV1 (%)70.0 (57.0-89.5)
FEV1/FVC (%)102.0 (93.2-111.0)
sPAP (mmHg)53 (44-69)
LVEF (%)60 (55-66)

: number; class 1: pulmonary arterial hypertension; class 2: PH related to left heart disease; class 3: PH related to pulmonary disease; class 4: thromboembolic PH; class 5: others; Hb: haemoglobin; RDW: red cell distribution width; PLTs: platelets; BNP: brain natriuretic peptide; DLCO: diffusion lung capacity for carbon monoxide; FEV1: forced expiratory volume in the 1st second; FVC: forced vital capacity; sPAP: systolic pulmonary artery pressure; LVEF: left ventricular ejection fraction.