Transcriptome Analysis of Hypertrophic Heart Tissues from Murine Transverse Aortic Constriction and Human Aortic Stenosis Reveals Key Genes and Transcription Factors Involved in Cardiac Remodeling Induced by Mechanical Stress

<div>Shared DEGs in the four datasets for the early stage of cardiac remodeling. (a) Venn diagram showed 251 shared DEGs. (b) Heatmap for 74 DEGs with same trends from the four datasets. (c) Network diagram of 74 DEGs with same trends in the early stage of cardiac remodeling. (d) Plotted biological processes for 74 DEGs.DEG: differential expression gene.</div>

Disease Markers

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Figure 1: Transcriptome Analysis of Hypertrophic Heart Tissues from Murine Transverse Aortic Constriction and Human Aortic Stenosis Reveals Key Genes and Transcription Factors Involved in Cardiac Remodeling Induced by Mechanical Stress 

Figure 1 | Transcriptome Analysis of Hypertrophic Heart Tissues from Murine Transverse Aortic Constriction and Human Aortic Stenosis Reveals Key Genes and Transcription Factors Involved in Cardiac Remodeling Induced by Mechanical Stress 