Transcriptome Analysis of Hypertrophic Heart Tissues from Murine Transverse Aortic Constriction and Human Aortic Stenosis Reveals Key Genes and Transcription Factors Involved in Cardiac Remodeling Induced by Mechanical Stress

<div>Prediction of the TFs of DEGs in mice and human hypertrophied heart induced by mechanical stress. (a) TFs involved in the early cardiac remodeling of mice. (b) TFs involved in the late cardiac remodeling of mice. (c) TFs involved in the hypertrophied patients. The red character showed the mutual TFs in the mice and human. DEG: differential expression gene; TF: transcription factor.</div>

Disease Markers

fig4

Figure 4

Figure 4: Transcriptome Analysis of Hypertrophic Heart Tissues from Murine Transverse Aortic Constriction and Human Aortic Stenosis Reveals Key Genes and Transcription Factors Involved in Cardiac Remodeling Induced by Mechanical Stress 

Figure 4 | Transcriptome Analysis of Hypertrophic Heart Tissues from Murine Transverse Aortic Constriction and Human Aortic Stenosis Reveals Key Genes and Transcription Factors Involved in Cardiac Remodeling Induced by Mechanical Stress 