Research Article

Transcriptome Analysis of Hypertrophic Heart Tissues from Murine Transverse Aortic Constriction and Human Aortic Stenosis Reveals Key Genes and Transcription Factors Involved in Cardiac Remodeling Induced by Mechanical Stress

Table 1

Studies that included murine model of cardiac remodeling induced by TAC using DNA microarray.

Accession numberStainDays post TACSample volumeCitationHypertrophic gene expression

GSE61177C57BL/63d4 vs 3[13]ElevatedEnrolled
GSE1621FVB10d4 vs 4[14]ElevatedEnrolled
GSE5500C57Bl6/J–FVB/N7d4 vs 6[15]ElevatedEnrolled
GSE415C57BL/67d4 vs 4[16]UnchangedExcluded
GSE5129C57BL/67d1 vs 1[17]Excluded for small sample size
GSE48110C57Bl/63d, 11d, &28d3 vs 3 for each time point[3]ElevatedEnrolled
GSE38733Not shown28d1 vs 1UnpublishedExclued for small sample size
E-MTAB-2732C57BL/6AmbiguousAmbiguousUnpublishedExclueded
GSE12337C57BL/628d4 vs 4[18]ElevatedEnrolled
GSE2459FVB30d9 vs 6[19]ElevatedEnrolled
GSE72904C57BL/628d3 vs 3UnpublishedElevatedEnrolled
GSE52796B6.12928d6 vs 9[20]ElevatedEnrolled
GSE68518Not shown28d4 vs 6[21]ElevatedEnrolled
GSE56348C57BL/628d5 vs 5[22]ElevatedEnrolled