Transcriptome Analysis of Hypertrophic Heart Tissues from Murine Transverse Aortic Constriction and Human Aortic Stenosis Reveals Key Genes and Transcription Factors Involved in Cardiac Remodeling Induced by Mechanical Stress
Table 2
GO items of the 16 shared DEGs with the same trends during the late stage of cardiac remodeling.
Term
Count
%
value
Genes
GO:0071260~cellular response to mechanical stimulus
4
25
NPPB, COL1A1, ANKRD1, NPPA
GO:0071560~cellular response to transforming growth factor beta stimulus
3
18.75
POSTN, COL1A1, ANKRD1
GO:0035582~sequestering of BMP in extracellular matrix
2
12.5
NBL1, FBN1
GO:0071356~cellular response to tumor necrosis factor