Patterns of TIGIT Expression in Lymphatic Tissue, Inflammation, and Cancer

Figure 5

Interindividual variations of TIGIT (green) and PD-1 (red) of (a) CD4⁺ helper T cells, (b) CD8⁺ cytotoxic T cells, and (c) FOXP3⁺ regulatory T cells among two patients (P1 and P2) with lung cancer and five patients (P1-5) with colorectal cancer. Relative expression refers to the fluorescence measurement in the tonsil germinal centre periphery (Ref. Gc. To.) set to 100%. The black bar shows the TIGIT : PD-1 expression ratio.

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