Research Article
Performance of a Novel Blood-Based Early Colorectal Cancer Screening Assay in Remaining Serum after the Blood Biochemical Test
Table 2
Results of ColoDefense in detecting colorectal cancer between different serum volumes.
| | Stages | Serum volume (mL) | | SDC2+ (%) | SEPT9+ (%) | SDC2 or SEPT9+ (%) |
| | I | <1.5 | 3 | 66.7 (2/3) | 33.3 (1/3) | 100.0 (3/3) | | 1.5-2.5 | 4 | 25.0 (1/4) | 25.0 (1/4) | 50.0 (2/4) | | >2.5 | 6 | 66.7 (4/6) | 50.0 (3/6) | 66.7 (4/6) |
| | II | <1.5 | 16 | 62.5 (10/16) | 75.0 (12/16) | 81.3 (13/16) | | 1.5-2.5 | 11 | 36.4 (4/11) | 81.8 (9/11) | 81.8 (9/11) | | >2.5 | 22 | 86.4 (19/22) | 86.4 (19/22) | 90.9 (20/22) |
| | III | <1.5 | 10 | 90.0 (9/10) | 70.0 (7/10) | 100.0 (10/10) | | 1.5-2.5 | 11 | 63.6 (7/11) | 63.6 (7/11) | 72.7 (8/11) | | >2.5 | 18 | 83.3 (15/18) | 72.2 (13/18) | 94.4 (17/18) |
| | IV | <1.5 | 4 | 75.0 (3/4) | 100.0 (4/4) | 100.0 (4/4) | | 1.5-2.5 | 3 | 100.0 (3/3) | 100.0 (3/3) | 100.0 (3/3) | | >2.5 | NA | NA | NA | NA |
| | Unknown | <1.5 | 2 | 50.0 (1/2) | 100.0 (2/2) | 100.0 (2/2) | | >2.5 | 1 | 100.0 (1/1) | NA | 100.0 (1/1) |
| | Total stages | <1.5 | 35 | 71.4 (25/35) | 74.3 (26/35) | 91.4 (32/35) | | 1.5-2.5 | 29 | 51.7 (15/29) | 69.0 (20/29) | 75.9 (22/29) | | >2.5 | 47 | 83.0 (39/47) | 74.5 (35/47) | 89.4 (42/47) |
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NA: not applicable.
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